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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM21A All Species: 14.85
Human Site: S877 Identified Species: 40.83
UniProt: Q641Q2 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q641Q2 NP_001005751.1 1341 147184 S877 L L E P S V G S L F G D D E D
Chimpanzee Pan troglodytes XP_001140122 1427 155633 S963 L L E P S V G S L F G D D E D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534948 1205 132612 V765 A R P K S T G V F Q D E E L L
Cat Felis silvestris
Mouse Mus musculus Q6PGL7 1334 145292 S873 S S V P S G G S L F G D D E D
Rat Rattus norvegicus Q80X08 1328 145131 S870 L S M P S G G S L F G D D D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234527 1326 146323 S872 L K P S S G G S I F G D D D E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001039320 401 44860
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBW7 1469 160880 C962 S S D Y G A M C L F S D V P P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800027 2367 254413 L1288 V P A R P P P L K F L T S K V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.3 N.A. 65.9 N.A. 73.5 72.7 N.A. N.A. 55.4 N.A. 21.7 N.A. 20.4 N.A. N.A. 24.1
Protein Similarity: 100 92.6 N.A. 70.6 N.A. 80.5 80 N.A. N.A. 68.7 N.A. 26.2 N.A. 36.6 N.A. N.A. 36.2
P-Site Identity: 100 100 N.A. 13.3 N.A. 73.3 73.3 N.A. N.A. 53.3 N.A. 0 N.A. 20 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 26.6 N.A. 73.3 80 N.A. N.A. 73.3 N.A. 0 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 12 0 0 12 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 0 0 0 0 0 0 12 67 56 23 45 % D
% Glu: 0 0 23 0 0 0 0 0 0 0 0 12 12 34 12 % E
% Phe: 0 0 0 0 0 0 0 0 12 78 0 0 0 0 0 % F
% Gly: 0 0 0 0 12 34 67 0 0 0 56 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 12 0 12 0 0 0 0 12 0 0 0 0 12 0 % K
% Leu: 45 23 0 0 0 0 0 12 56 0 12 0 0 12 12 % L
% Met: 0 0 12 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 23 45 12 12 12 0 0 0 0 0 0 12 12 % P
% Gln: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % Q
% Arg: 0 12 0 12 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 23 34 0 12 67 0 0 56 0 0 12 0 12 0 0 % S
% Thr: 0 0 0 0 0 12 0 0 0 0 0 12 0 0 0 % T
% Val: 12 0 12 0 0 23 0 12 0 0 0 0 12 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _